中国科技期刊卓越行动计划推介：Brain Network Disorders | 1卷第2期

01

Review Articles

1

Targeting the centromedian nucleus of the thalamus for epilepsy

DBS治疗癫痫的潜在突破点：丘脑中央中核 |

西班牙University Hospital La Princesa医院Cristina Virgina Torres Díaz团队

This study focuses on advanced methods for centromedian nucleus localization in DBS, demonstrating their utility in enhancing targeting precision for drug-resistant epilepsy.

复制链接阅读原文▼https://www.sciencedirect.com/science/article/pii/S3050623924000178

2

The role of the JAK2-mediated inflammatory pathway in ischemic stroke

JAK2炎症通路：缺血性脑卒中的关键机制探索 |

美国纽约州立大学石溪分校Ke Jian Liu教授与宣武医院戚智锋教授团队

This review summarizes the JAK2-mediated inflammatory pathway in ischemic stroke, highlighting the potential of JAK2 inhibitors to enhance recanalization therapy by alleviating post-reperfusion injury.

复制链接阅读原文▼

3

Biomarkers on anti-N-methyl-D-aspartate receptor encephalitis

抗NMDAR脑炎的生物标志物的“前世今生” |

广州市第一人民医院汪鸿浩教授团队

This review synthesizes biomarkers of anti-NMDAR encephalitis, aiming to elucidate mechanisms and highlighting NMDAR subunits, antibodies, inflammatory factors, and clinical correlates.

4

Research progress in predictive techniques for early neurological deterioration in acute ischemic stroke

急性缺血性卒中早期神经功能恶化如何预测？ |

南京医科大学第一附属医院言克莉团队

This review explores advances in prediction tools for early neurological deterioration in acute ischemic stroke to aid risk stratification and foster research development.

02

Original Articles

1

Acute temporal lesions are associated with phonological word verification errors

语言障碍新视角探索急性颞叶损伤 |

美国约翰霍普金斯大学医学院Argye E. Hillis教授团队

This investigation provides evidence for the role of the superior temporal lobe in phonological processing during spoken word recognition and clarifies the lateralization distribution at the population level.

2

LC3-associated endocytosis facilitates extracellular Tau aggregate internalization and degradation in microglia

小胶质细胞与LC3相关内吞作用： Tau 蛋白的 “清除卫士” |

印度国家精神健康和神经科学研究所Subashchandrabose Chinnathambi教授团队

This study reveals that LANDO-mediated lysosomal degradation of extracellular Tau by microglia limits Tau spreading, proposing a novel mechanism for regulating Tauopathy in AD.

3

Compound muscle action potentials in the median/accessory nerves reflect disease severity in amyotrophic lateral sclerosis

渐冻症“晴雨表“：正中/副神经复合肌肉动作电位 |

武汉大学人民医院卢祖能、翁超教授团队

This study shows CMAP amplitudes of median and accessory nerves correlate with ALSFRS-R scores, suggesting their utility for early ALS diagnosis.